Description
Product Overview
4-Amino-2-chloropyridine is an aromatic nitrogen-containing compound used as an intermediate in the chemical industry. Its defined molecular structure and reactive functional groups make it suitable for further chemical transformation in the development and production of pharmaceutical, pesticide, and pigment-related compounds.
Also identified as 2-chloropyridin-4-amine, this compound provides both an amino group and a chloro-substituted pyridine ring, offering useful reactivity for downstream synthesis. For manufacturers and chemical buyers, accurate identification is important when evaluating raw materials for laboratory development, process research, and commercial production.
Chemical Identification
The chemical is commonly referred to as 4-Amino-2-chloropyridine, while its IUPAC name is 2-chloropyridin-4-amine. Other recognized names include 2-Chloropyridin-4-amine, 2-Chloro-4-aminopyridine, and 2-Chloro-pyridin-4-ylamine.
| Property | Specification |
|---|---|
| Product Name | 4-Amino-2-chloropyridine |
| CAS Number | 14432-12-3 |
| IUPAC Name | 2-chloropyridin-4-amine |
| Molecular Formula | C5H5ClN2 |
| Molecular Weight | 128.56 g/mol |
| Synonyms | 2-Chloro-4-aminopyridine, 2-Chloropyridin-4-amine |
Using both the CAS number 14432-12-3 and the product name during procurement can help buyers confirm the intended material when reviewing supplier catalogs, technical documents, specifications, and purchasing records.
Molecular Structure and Chemical Reactivity
The structure of 4-Amino-2-chloropyridine contains a pyridine ring substituted with amino and chloro groups. This combination gives the molecule useful chemical characteristics for further synthetic modification. The amino functionality can participate in a range of chemical transformations, while the chloro substituent can provide another position for selective reactions depending on the synthesis route.
For process developers, understanding these functional groups is useful when assessing the compound as a pharmaceutical intermediate or as a starting material for other specialty chemicals. The actual reaction pathway, reagent selection, and processing conditions should be established according to the target compound and validated manufacturing procedure.
Applications in Pharmaceutical Intermediates
One of the primary applications of 4-Amino-2-chloropyridine is its use as an intermediate in pharmaceutical synthesis. Pyridine-based structures are widely incorporated into medicinal chemistry because their nitrogen-containing aromatic framework can contribute specific chemical and functional properties to target molecules.
For pharmaceutical manufacturers and research organizations, an intermediate must provide more than a suitable molecular structure. Consistent identity, appropriate quality specifications, analytical documentation, and dependable supply are important when moving from research-scale synthesis toward repeated production.
4-Amino-2-chloropyridine can therefore be evaluated according to the requirements of the intended synthesis. Buyers should establish their required specification and analytical criteria before purchasing, particularly when the material will be incorporated into a controlled manufacturing process.
Use in Pesticide Intermediate Synthesis
The compound is also used as an intermediate for pesticide-related chemical synthesis. Its substituted pyridine structure provides a useful foundation for further molecular modification, allowing chemists to develop compounds with different functional groups and performance characteristics.
In pesticide intermediate procurement, consistency is particularly important because changes in starting-material quality can influence downstream reaction performance. Manufacturers should therefore evaluate the material against their internal specifications and confirm the relevant analytical documentation before introducing it into production.
The suitability of 4-Amino-2-chloropyridine ultimately depends on the specific synthesis route and target molecule. It should be selected according to the technical requirements of the process rather than simply by application category.
Application in Pigment Chemistry
Another application area is pigment intermediate production. Specialty pigments often require carefully controlled synthetic routes in which intermediate materials contribute to the final molecular structure. A suitable pyridine-based intermediate can therefore have value in specific pigment development and manufacturing processes.
For buyers operating in this field, reliable chemical identification is an essential first step. The CAS number 14432-12-3 provides a standardized reference that can help purchasing teams communicate accurately with suppliers and distinguish the required material from similarly named pyridine derivatives.
Key Considerations for Industrial Buyers
When sourcing 4-Amino-2-chloropyridine, buyers should consider technical and commercial factors together. Chemical identity should be confirmed first, followed by quality requirements, analytical testing, packaging, quantity, lead time, and documentation.
A well-prepared purchasing inquiry can include the CAS 14432-12-3, required quantity, target specification, intended application, delivery destination, and documentation requirements. Providing these details helps suppliers understand the project more accurately and can make quotation and qualification more efficient.
| Purchasing Factor | Recommended Focus |
|---|---|
| Chemical identity | 4-Amino-2-chloropyridine, CAS 14432-12-3 |
| Quality | Customer-defined specification and testing |
| Documentation | Technical and safety documentation |
| Quantity | Laboratory, pilot, or production requirement |
| Packaging | Appropriate packaging for storage and transport |
| Delivery | Lead time and destination requirements |
Selecting a Reliable Chemical Supplier
For overseas customers, supplier selection should extend beyond the availability of a product listing. A suitable supplier should be able to provide clear product identification and relevant technical information while maintaining consistent communication throughout the purchasing process.
This is particularly important when 4-Amino-2-chloropyridine is used as a pharmaceutical, pesticide, or pigment intermediate. The requirements of each downstream process can differ considerably, so buyers should communicate their technical expectations before confirming an order.
A professional sourcing process also helps buyers establish a clearer basis for repeat procurement. Once the material has been qualified internally, maintaining consistent specifications and supply conditions can simplify subsequent purchasing and production planning.
Supporting Downstream Chemical Development
The value of an intermediate lies in how effectively it supports the next stage of synthesis. 4-Amino-2-chloropyridine offers a useful combination of pyridine-ring chemistry and functional-group reactivity, making it relevant to several specialty chemical applications.
For research and production teams, the most practical approach is to evaluate the material according to the desired downstream transformation. Reaction compatibility, purity requirements, analytical controls, and process conditions should all be considered before selecting a commercial grade or establishing purchasing specifications.
With clear identification and application-focused evaluation, 4-Amino-2-chloropyridine CAS 14432-12-3 can serve as a practical intermediate for manufacturers developing pharmaceutical, pesticide, and pigment-related compounds.
Conclusion
4-Amino-2-chloropyridine is a versatile pyridine-based chemical intermediate identified by CAS 14432-12-3. Its molecular structure, containing amino and chloro substituents, provides useful opportunities for further chemical transformation.
Its applications in pharmaceutical, pesticide, and pigment intermediate synthesis make accurate sourcing important for chemical manufacturers and research organizations. By confirming chemical identity, defining quality requirements, reviewing documentation, and evaluating supplier capability, buyers can establish a more reliable foundation for downstream chemical production.
For industrial procurement, using the product name together with CAS 14432-12-3 is a straightforward way to improve communication and reduce ambiguity when requesting technical information or quotations.
FAQ
What is 4-Amino-2-chloropyridine?
4-Amino-2-chloropyridine is a pyridine-based organic compound used as an intermediate in pharmaceutical, pesticide, and pigment-related chemical synthesis.
What is the CAS number of 4-Amino-2-chloropyridine?
The CAS number is 14432-12-3.
What is the molecular formula?
The molecular formula of 4-Amino-2-chloropyridine is C5H5ClN2, with a molecular weight of 128.56 g/mol.
What are the alternative names?
Common names include 2-chloropyridin-4-amine, 2-Chloro-4-aminopyridine, and 2-Chloro-pyridin-4-ylamine.
What is 4-Amino-2-chloropyridine used for?
It is used as an intermediate in pharmaceuticals, pesticides, and pigments, where its substituted pyridine structure can support further chemical synthesis.
What should buyers confirm before sourcing it?
Buyers should confirm the CAS number, product identity, required quality specification, analytical documentation, quantity, packaging, lead time, and delivery requirements before placing an order.

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